Oral Medications for ED

Erectile dysfunction (ED) is a common condition that affects many men. Oral medications are a safe and effective treatment option. These medications work by increasing blood flow to the penis, helping to achieve and maintain an erection when sexually stimulated.

• Takes effect in 30–60 minutes
• Best taken on an empty stomach
• Lasts 4–6 hours
• Avoid with heavy meals or excessive alcohol

• Takes effect in 30–60 minutes
• Can be taken with or without food
• Lasts up to 36 hours ("The weekend pill")
• Available in daily low-dose form for continuous effect

✔ Take the medication before planned sexual activity (time varies by drug).
✔ Sexual stimulation is still required for the medication to work.
✔ Do not take more than one dose in a 24-hour period (except for daily tadalafil).
✔ Avoid excessive alcohol as it may reduce effectiveness and increase side effects.

Most men tolerate ED medications well, but some may experience:

• Headache
• Flushing (warmth, redness in the face)
• Nasal congestion
• Upset stomach or indigestion
• Dizziness or lightheadedness
• Muscle or back pain (more common with tadalafil)
• Blurred vision or changes in color perception (rare)

These medications are not safe for everyone. Avoid them if you:

• Take nitrates (e.g., nitroglycerin) for heart disease
• Have severe heart disease or recent stroke/heart attack
• Have uncontrolled high or low blood pressure
• Have severe liver or kidney disease

*** Go to the ER if you experience:

• A painful or prolonged erection lasting more than 4 hours (priapism)
• Severe chest pain or fainting after taking the medication
• Sudden vision or hearing loss

If you have any concerns or need help choosing the right medication, discuss it with your healthcare provider.